CATCH ME
Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly (CATCH ME)
Summary
CATCH ME aims to improve the prevention and treatment of atrial fibrillation and its complications. The goal is to develop and validate better disease management strategies based on the improved understanding of the main health modifiers (such as genes, drugs, and behaviour) leading to atrial fibrillation in the European population.
The CATCH ME partners combine excellence in clinical practice, translational pathophysiology, genetics, bioengineering, epidemiology and biostatistics with competence in the development of cardiovascular practice guidelines. As a consortium, CATCH ME also has access to large sets of human biological specimens (atrial tissue and blood samples) and carefully phenotyped patient populations. This is the basis to define the major causes and risk factors (“health modifiers”) of AF in Europe and characterise distinct clinical types of AF to advance future personalised strategies for prevention, diagnosis, and treatment of AF patients. AFNET will bring its competence in ethical issues as well as training programs and science communication in order to disseminate and popularize the results.
Publication
Zeemering S, Isaacs A, Winters J, Maesen B, Bidar E, Dimopoulou C, Guasch E, Batlle M, Haase D, Hatem S, Kara M, Kääb S, Mont L, Sinner M, Wakili R, Maessen J, Crijns HJGM, Fabritz L, Kirchhof P. Stoll M, Schotten S. Atrial fibrillation in the presence and absence of heart failure enhances expression of genes involved in cardomyocyte structure, conduction properties, fibrosis, inflammation, and endothelial dysfunction. HeartRhythm Journal, 21 August 2022. doi: 10.1016/j.hrthm.2022.08.019
Current status
Project start:
21.05.2015
Project end:
30.04.2019
CATCH ME Consortium
- University of Birmingham, UK
- Universidad de Barcelona, Spain
- Maastricht University, The Netherlands
- Ludwig-Maximilians University Munich und German Centre for Cardiovascular Research (DZHK), Germany
- University of Oxford, UK
- Université Pierre et Marie Curie, France
- Atrial Fibrillation Network (AFNET), Germany
- European Society of Cardiology (ESC), France
Coordinating Investigator
Prof. Dr. Paulus Kirchhof, Birmingham, UK
Funding
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 633196 (CATCH ME)
Contact
Atrial Fibrillation NETwork (AFNET)
Mendelstraße 11
48149 Münster, Germany
Phone: +49 251 980 1330
Fax: +49 251 980 1349
Email: info[at]kompetenznetz-vorhofflimmern.de