Completed studies and registries

Completed clinical trials

AXAFA – AFNET 5 Trial
Anticoagulation using the direct factor Xa inhibitor apixaban during Atrial Fibrillation catheter Ablation: Comparison to vitamin K antagonist therapy.

RE-LATED AF – AFNET 7 Trial
Resolution of Left Atrial-Appendage Thrombus – Effects of Dabigatran in patients with Atrial Fibrillation (RE-LATED AF) 

Flec-SL – AFNET 3 Trial
Targeted pharmacological reversal of electrical remodeling after cardioversion of atrial fibrillation; randomized controlled clinical trial

ANTIPAF – AFNET 2 Trial
Angiotensin II receptor antagonist (Olmesartan) for treatment of paroxysmal atrial fibrillation

Gap-AF – AFNET 1 Trial
Catheter ablation of atrial fibrillation by linear pulmonary vein isolation

BACE-PACE Trial
Pacemaker stimulation for prevention of paroxysmal atrial fibrillationn
 

Completed registries

AFNET 2-Register (EORP) für Vorhofflimmern
German armof the EORP AF General Registry

IMPULS Studie
Individual management of patients with non-permanent atrial fibrillation using Dronedarone: prospective non-interventional study (NIS) within outpatient care

Basis-AF Register
central patient registry

Cath-AF Register
Catheter ablation registry

CEC-AF Register
Assessment of complications within the central patient registry / Critical Event Committee (CEC)

Cost-AF Register
Health economics in patients with atrial fibrillation

QoL-AF Register
Quality of Life evaluation of AFNET trials and registries

Surg-AF Register
Surgical ablation registry

Effects of alcohol consumption on atrial fibrillation

KORA-AF Event
Prevalence of atrial fibrillation in a representative sample of the general population (KORA-AF EVENT)

Atrial fibrillation and the risk of neurological complications

Other completed projects

Characterizing Atrial fibrillation by Translating its Causes into Health Modifiers in the Elderly (CATCH ME) (EU research consortium)
 

Contractile remodeling in atrial fibrillation: Mechanisms and therapeutic approaches
 

Electrical remodeling and effects of pharmaceuticals on chronic atrial fibrillation
 

Genetic determinants of atrial fibrillation
 

Molecular and electrophysiological causes of spontaneous atrial fibrillation in a transgenic model (CREM-transgenic mouse)
 

Molecular signal transduction pathways in atrial cardiomyocytes and their interaction with the interstitial matrix during atrial fibrillation
 

Regulation of ion channel proteins in early phases of atrial fibrillation
 

New diagnostic imaging techniques

CHARGE-AF, ENAFRA, EUTRAF (International Research Cooperations)